Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders

Individuals with congenital indifference to pain have painless injuries beginning in infancy but otherwise normal sensory responses upon examination. Perception of passive movement, joint position, and vibration is normal, as are tactile thresholds and light touch perception. There is intact ability to distinguish between sharp and dull stimuli and to detect differences in temperature. The insensitivity to pain does not appear to be due to axonal degeneration, as the nerves appear to be normal upon gross examination (8). The complications of the disease follow the inability to feel pain, and most individuals will have injuries to lip or tongue caused by biting themselves in the first 4 years of life. Patients have frequent bruises and cuts, usually have a history of fractures that go unnoticed, and are often only diagnosed because of limping or lack of use of a limb. The literature contains very colorful descriptions of patients with congenital inability to perceive any form of pain.

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Should fish feel pain? A plant perspective by by František Baluška

Plants are not usually thought to be very active behaviorally, but the evidence suggests otherwise. Moreover, in stressful situations, plants produce numerous chemicals that have painkilling and anesthetic properties. Finally, plants, when treated with anesthetics, cannot execute active behaviors such as touch-induced leaf movements or rapid trap closures after localizing animal prey

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Against functionalism: why I think the Foundational Research Institute should rethink its approach, by Michael Edward Johnson

FRI believes in analytic functionalism, or what David Chalmers calls “Type-A materialism”. Essentially, what this means is there’s no ’theoretical essence’ to consciousness; rather, consciousness is the sum-total of the functional properties of our brains. Since ‘functional properties’ are rather vague, this means consciousness itself is rather vague, in the same way words like “life,” “justice,” and “virtue” are messy and vague.

And if consciousness is all these things, so too is suffering. Which means suffering is computational, yet also inherently fuzzy, and at least a bit arbitrary; a leaky high-level reification impossible to speak about accurately, since there’s no formal, objective “ground truth”.

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Physical theories of consciousness reduce to panpsychism, by Michael St. Jules

The necessary features for consciousness in prominent physical theories of consciousness that are actually described in terms of physical processes do not exclude panpsychism, the possibility that consciousness is ubiquitous in nature, including in things which aren’t typically considered alive. I’m not claiming panpsychism is true, although this significantly increases my credence in it, and those other theories could still be useful as approximations to judge degrees of consciousness. Overall, I’m skeptical that further progress in theories of consciousness will give us plausible descriptions of physical processes necessary for consciousness that don’t arbitrarily exclude panpsychism, whether or not panpsychism is true.

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Consciousness Realism: the non-eliminativist view of consciousness, by Magnus Vinding

The non-eliminativist view of consciousness is the view that consciousness is real and that its existence cannot reasonably be doubted. All the beliefs we are aware of appear in consciousness, and hence to express disbelief in the existence of consciousness amounts to reading off and trusting at least some aspect of one’s conscious experience – the thing believed not to exist – which renders such disbelief nonsensical. To deny the existence of consciousness, the non-eliminativist position holds, is to deny one’s own existence. At most, one can utter the words.

What Does Consciousness Realism Entail? To be a realist about consciousness is to insist that whether someone is conscious, and what their conscious experience is like, is a fact of the world. If someone is experiencing torture, there is no amount of interpretation an outside observer can make that changes what it is like to undergo that experience. The experience is an inherent property of the world, like physical pressure, that is independent of external observers. It is an objective fact of the world that subjective, first-person facts are a feature of reality.

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David Pearce on what is the difference between perception and consciousness

“Thus the existence of a real object outside me is never given directly in perception, but can only be added in thought to what is a modification of inner sense as its external cause, and hence can only be inferred.”
(Kant, Critique of Pure Reason, 1781)

“All that we see or seem is but a dream within a dream.”
(Edgar Allan Poe)

“Perception” is a useful word. It’s also systematically misleading. This is because the term suggests that each of us enjoys direct access to our local surroundings, including one’s extra-cranial body. “Cross-modally matched real-time egocentric world-simulation” might be more apt; alas, it’s a mouthful. Either way, the external environment may be inferred; it’s not accessed. The mind-independent world powerfully selects the subjective content of one’s waking world-simulation; the mind-independent world doesn’t create it.

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David Conner on entity and agency

Agency is the capacity for some entity to be considered an independent actor with the ability to interact on our shared sociophysical fabric. Agents process information signals from their environment, which can be conceptualized as sensory input or data. These sensory perceptions are internalized into information representations.

Entities with agency can analyze and process these to inform its actions. Agents have a degree of autonomy but do not exist in isolation. They must have independence and the ability to influence their environment. They may or may not be self-aware. They may understand the exact consequences of their actions or may not, but it is impossible for any entity to fully understand its influence on its environment, regardless of how self-aware it is.

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Synesthesia as unusual sense, by Craig Weinberg

“The fact of synesthesia (the experience of multiple and unusual sense modalities associated with events that are commonly experienced with one sense modality) shows that there need not be any connection between physical conditions and consciousness. Someone might play a piano and see musical notes at the same time, and that would be a form of synesthesia, but they are still seeing something visible and hearing something audible. I think it’s useful to distinguish visible (Aesthetic Qualia) from optical (Anesthetic Physical Mechanism) and audible (AQ) from sonic (APM). All sense qualia can be separated from physics or information this way.”

Post by Craig Weinberg

Stefano Mancuso on the secret life of plants: how they memorise, communicate, problem solve and socialise

One of the most controversial aspects of Mancuso’s work is the idea of plant consciousness. As we learn more about animal and plant intelligence, not to mention human intelligence, the always-contentious term consciousness has become the subject of ever more heated scientific and philosophical debate. “Let’s use another term,” Mancuso suggests. “Consciousness is a little bit tricky in both our languages. Let’s talk about awareness. Plants are perfectly aware of themselves.” A simple example is when one plant overshadows another – the shaded plant will grow faster to reach the light. But when you look into the crown of a tree, all the shoots are heavily shaded. They do not grow fast because they know that they are shaded by part of themselves. “So they have a perfect image of themselves and of the outside,” says Mancuso.

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